Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530174 | 0.97 | LMNA (0.39) | LMNAP2RY10 | |
| SCHEMBL6529141 | 0.90 | RARB (0.38) | LMNAFFAR1MMP12PTGESALOX5 | |
| SCHEMBL6527581 | 0.87 | MMP12 (0.36) | LMNAMMP12P2RY10 | |
| SCHEMBL6530514 | 0.86 | FDFT1 (0.41) | LMNAMMP12PTGESALOX5PPARG | |
| SCHEMBL6528235 | 0.84 | S1PR1 (0.46) | LMNAFFAR1PTGESALOX5PPARG | |
| SCHEMBL6530119 | 0.83 | S1PR1 (0.44) | LMNAMMP12PPARGACACB | |
| SCHEMBL6529689 | 0.83 | LMNA (0.37) | LMNAFFAR1MMP12PTGESALOX5 | |
| SCHEMBL6504727 | 0.82 | S1PR1 (0.45) | MMP12 | |
| SCHEMBL6529005 | 0.82 | PTPN11 (0.40) | LMNAP2RY10 | |
| SCHEMBL6529532 | 0.82 | S1PR1 (0.44) | FFAR1MMP12PTGESALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |