Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530119 | 0.90 | S1PR1 (0.44) | S1PR1MMP12PTPN1PTPN6PTPN11 | |
| SCHEMBL6532172 | 0.86 | LTA4H (0.42) | PTPN1PTPN6PTPN11PDE4APDE4B | |
| SCHEMBL6502328 | 0.86 | RARB (0.42) | S1PR1RARBRARAPTGESALOX5 | |
| SCHEMBL6528235 | 0.85 | S1PR1 (0.46) | S1PR1RARBRARAPTPN11PTGES | |
| SCHEMBL6530514 | 0.85 | FDFT1 (0.41) | MMP12PTGESALOX5PPARG | |
| SCHEMBL6527581 | 0.84 | MMP12 (0.36) | S1PR1RARBMMP12LTA4HS1PR2 | |
| SCHEMBL6504727 | 0.83 | S1PR1 (0.45) | S1PR1RARBRARARARGMMP12 | |
| SCHEMBL6529689 | 0.82 | LMNA (0.37) | RARBRARAMMP12PTPN11PTGES | |
| SCHEMBL6529753 | 0.82 | PPARG (0.34) | RARBPTPN11PTGESALOX5PPARG | |
| SCHEMBL6529141 | 0.81 | RARB (0.38) | S1PR1RARBMMP12PTPN11PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |