Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499997 | 0.87 | LMNA (0.36) | MMP12LMNAP2RY10 | |
| SCHEMBL6529141 | 0.86 | RARB (0.38) | MMP12RARBLMNAS1PR1 | |
| SCHEMBL6530514 | 0.85 | FDFT1 (0.41) | MMP12LMNA | |
| SCHEMBL6504727 | 0.85 | S1PR1 (0.45) | MMP12RARBS1PR2S1PR1 | |
| SCHEMBL6529532 | 0.84 | S1PR1 (0.44) | MMP12RARBS1PR2S1PR1LTA4H | |
| SCHEMBL6530119 | 0.84 | S1PR1 (0.44) | MMP12LMNAS1PR1 | |
| SCHEMBL6530174 | 0.83 | LMNA (0.39) | RARBLMNAP2RY10S1PR2S1PR1 | |
| SCHEMBL6529689 | 0.82 | LMNA (0.37) | MMP12RARBLMNAP2RY10 | |
| SCHEMBL6528235 | 0.82 | S1PR1 (0.46) | RARBLMNAS1PR1 | |
| SCHEMBL6529753 | 0.81 | PPARG (0.34) | RARBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |