Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499997 | 0.97 | LMNA (0.36) | LMNAP2RY10 | |
| SCHEMBL6529141 | 0.87 | RARB (0.38) | LMNAS1PR1S1PR3RARBPTPN11 | |
| SCHEMBL6504727 | 0.85 | S1PR1 (0.45) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL6529005 | 0.84 | PTPN11 (0.40) | LMNATHRBTHRAP2RY10S1PR1 | |
| SCHEMBL6527581 | 0.83 | MMP12 (0.36) | LMNAP2RY10S1PR1S1PR2RARB | |
| SCHEMBL6530514 | 0.83 | FDFT1 (0.41) | LMNA | |
| SCHEMBL6532172 | 0.82 | LTA4H (0.42) | THRBTHRACNR2PTPN11 | |
| SCHEMBL6530992 | 0.82 | LMNA (0.40) | LMNAP2RY10MMP9MMP8MMP13 | |
| SCHEMBL6528235 | 0.81 | S1PR1 (0.46) | LMNAS1PR1S1PR3CNR2RARB | |
| SCHEMBL6530119 | 0.80 | S1PR1 (0.44) | LMNAS1PR1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |