Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501353 | 0.83 | L3MBTL1 (0.50) | L3MBTL1ALOX15HPGDPOLBMAPT | |
| SCHEMBL12961921 | 0.82 | POLB (0.45) | L3MBTL1HPGDPOLBTSHRALDH1A1 | |
| SCHEMBL6500450 | 0.81 | HPGD (0.63) | L3MBTL1ALOX15HPGDPOLBMAPT | |
| Hydrochloric Acid SCHEMBL2267196 | 0.81 | ALDH1A1 (0.54) | HPGDPOLBMAPTTSHRALDH1A1 | |
| SCHEMBL27475382 | 0.79 | GSK3B (0.55) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL7655624 | 0.77 | RAB9A (0.61) | L3MBTL1ALOX15HPGDPOLBMAPT | |
| SCHEMBL12245094 | 0.75 | CCNE2 (0.40) | ALOX15HPGDTSHRHDAC1ALDH1A1 | |
| SCHEMBL5270246 | 0.75 | NPC1 (0.57) | HPGDMAPTHDAC1ALDH1A1RAB9A | |
| SCHEMBL8220270 | 0.75 | GAA (0.45) | L3MBTL1ALOX15HPGDMAPTTSHR | |
| SCHEMBL12629900 | 0.74 | ALOX15 (0.55) | L3MBTL1ALOX15HPGDMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | L3MBTL1 2494/4885ALOX15 1656/4885HPGD 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.