Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502145 | 0.83 | NPC1 (0.50) | KMT2AEPHX2NPC1RAB9AMEN1 | |
| SCHEMBL6509220 | 0.83 | NPC1 (0.48) | PRMT3KMT2APDGFRANPC1RAB9A | |
| SCHEMBL6503922 | 0.81 | EPHX1 (0.51) | EPHX2NPC1RAB9AEPHX1ALDH1A1 | |
| SCHEMBL6504671 | 0.81 | EPHX1 (0.51) | EPHX2NPC1RAB9AEPHX1ALDH1A1 | |
| SCHEMBL6506236 | 0.80 | LMNA (0.43) | TDP1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL6509241 | 0.78 | KMT2A (0.36) | PRMT3TDP1KMT2AGAAEPHX2 | |
| SCHEMBL6499488 | 0.78 | KMT2A (0.56) | TDP1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL6500692 | 0.78 | RAB9A (0.52) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL6502232 | 0.78 | KMT2A (0.50) | KMT2AGAAEPHX2NPC1RAB9A | |
| SCHEMBL10249415 | 0.78 | EPHX1 (0.34) | KMT2AEPHX2NPC1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | S1PR2 750/4885PRMT3 1453/4885TDP1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.