Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.49 |
| ▸ | ACACA | Q13085 | 3/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507158 | 0.84 | RARB (0.45) | MMP12 | |
| SCHEMBL6505456 | 0.82 | SLC13A5 (0.48) | ACACBACACAFDFT1SLC13A5RXRA | |
| SCHEMBL6505903 | 0.80 | MMP12 (0.64) | ACACBFDFT1MMP12FFAR1 | |
| SCHEMBL6502683 | 0.80 | FFAR1 (0.48) | ACACBACACASLC13A5RXRARXRB | |
| SCHEMBL6530514 | 0.77 | FDFT1 (0.41) | ACACBACACAFDFT1SLC13A5MMP12 | |
| SCHEMBL9253929 | 0.74 | LMNA (0.58) | ACACBACACARXRARXRBNR1H4 | |
| SCHEMBL23590265 | 0.74 | RXRA (0.59) | ACACBACACARXRARXRBNR1H4 | |
| SCHEMBL6499912 | 0.73 | CYP4F2 (0.53) | ACACBCYP2D6FFAR1 | |
| SCHEMBL2568516 | 0.72 | SMN1; SMN2 (0.53) | FDFT1SLC13A5NR1H4CYP2D6 | |
| SCHEMBL6528364 | 0.72 | S1PR1 (0.61) | SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |