SCHEMBL650588

SCHEMBL650588

CC1c2ccccc2-c2cccc([Zr](Cl)(Cl)c3cccc4c3C(C)c3ccccc3-4)c21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.34
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A3 O75751 1/20 0.32
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
HTR2A P28223 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416194 0.76 LMNA (0.36) HTR2BHTR2A
SCHEMBL8581361 0.76 GPR3 (0.30) GPR3
SCHEMBL12429503 0.76 GPR3 (0.38) GPR3SLC22A2SLC22A3HTR7HTR2B
SCHEMBL358532 0.73 GPR3 (0.39) GPR3HTR7HTR2BHTR2A
SCHEMBL31338566 0.73 GPR3 (0.39) GPR3HTR7HTR2BHTR2A
Hydrochloric Acid SCHEMBL28225814 0.73 GPR3 (0.39) GPR3DRD2DRD4SLC22A2SLC22A3
SCHEMBL7176731 0.72
SCHEMBL28807674 0.72 GPR3 (0.38) GPR3DRD2DRD4SLC22A2SLC22A3
SCHEMBL30987013 0.72 ALDH1A1 (0.41) GPR3HTR7HTR2BHTR2APOLB
SCHEMBL29285278 0.72 ALDH1A1 (0.41) GPR3HTR7HTR2BHTR2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705851-B9 Catalyst systems and process for producing broad molecular weight distribution polyolefin CONOCOPHILLIPS CO (US) 2004-08-11 EP claimed
EP-0705851-B1 Catalyst systems and process for producing broad molecular weight distribution polyolefin CONOCOPHILLIPS CO (US) 2004-01-21 EP claimed
US-5594078-A BRIDGED FLUORENYL METALLOCENE CATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-01-14 US claimed
US-5534473-A METALLOCENES AND COCATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-07-09 US claimed
EP-0705851-A2 Catalyst systems and process for producing broad molecular weight distribution polyolefin PHILLIPS PETROLEUM COMPANY (US) 1996-04-10 EP claimed
EP-1852408-B1 PROCESS FOR THE DIMERIZATION OF ALPHA-OLEFINS IDEMITSU KOSAN CO (JP) 2018-04-04 EP disclosed
US-20130225892-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed
US-20120088946-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2012-04-12 US disclosed
US-8119850-B2 Process for producing unsaturated hydrocarbon compound IDEMITSU KOSAN CO., LTD. (JP) 2012-02-21 US disclosed
US-20090069614-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20090030255-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2009-01-29 US disclosed
EP-1852408-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-11-07 EP disclosed
EP-1849757-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030255-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR3 2942/4885DRD2 978/4885DRD4 818/4885
US-20090069614-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND AHR, ALOX12, ARNT GPR3 2030/4885DRD2 1042/4885DRD4 1034/4885
US-20120088946-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR3 2942/4885DRD2 978/4885DRD4 818/4885
US-20130225892-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR3 2942/4885DRD2 978/4885DRD4 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.