Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511310 | 0.85 | KMT2A (0.54) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6510588 | 0.85 | LMNA (0.50) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6510506 | 0.84 | MAPK1 (0.56) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6513739 | 0.81 | SMN1; SMN2 (0.42) | LMNAKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL6508617 | 0.80 | SIGMAR1 (0.46) | KMT2AMAPTCYP1A2SIGMAR1GRIN2D | |
| SCHEMBL6518559 | 0.79 | SMN1; SMN2 (0.55) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6515320 | 0.75 | SIGMAR1 (0.46) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5923353 | 0.75 | SMN1; SMN2 (0.48) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6507406 | 0.75 | RAB9A (0.52) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27341477 | 0.74 | ALDH1A1 (0.60) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |