Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373266 | 1.00 | PTGS1 (0.70) | PTGS1PTGS2CA2MAPTTDP1 | |
| SCHEMBL21786210 | 0.78 | PTGS1 (0.68) | PTGS1PTGS2MAPTTDP1ALDH1A1 | |
| SCHEMBL11180141 | 0.78 | PTGS2 (0.55) | PTGS1PTGS2CA2 | |
| SCHEMBL28027003 | 0.77 | PTPN1 (0.54) | PTGS1PTGS2CA2MAPTALDH1A1 | |
| SCHEMBL21786248 | 0.74 | SLC22A12 (0.48) | PTGS1PTGS2MAPTTDP1ALDH1A1 | |
| SCHEMBL4968060 | 0.73 | PTGS1 (0.50) | PTGS1PTGS2CA2KMT2AMEN1 | |
| SCHEMBL12054691 | 0.72 | CA2 (0.66) | PTGS1PTGS2CA2MAPTKMT2A | |
| SCHEMBL10622905 | 0.72 | CA2 (0.61) | PTGS1PTGS2CA2SMN1; SMN2 | |
| SCHEMBL6517495 | 0.71 | CA2 (0.56) | PTGS1PTGS2CA2ALDH1A1L3MBTL1 | |
| SCHEMBL4972432 | 0.71 | PTGS1 (0.70) | PTGS1PTGS2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| CN-117986154-A | Antiparasitic compounds | 英特维特国际股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | INTERVET INC. (US) | 2024-02-08 | — | — | US | disclosed |
| US-20240043385-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE | INTERVET INC. (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4284509-A1 | ANTIPARASITIC COMPOUNDS | Intervet International B.V. (NL) | 2023-12-06 | — | — | EP | disclosed |
| CN-116964031-A | Antiparasitic compounds | 英特维特国际股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230148316-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE | INTERVET INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230110397-A1 | ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE | INTERVET INC. (US) | 2023-04-13 | — | — | US | disclosed |
| EP-2545777-B2 | Use of an isoxazoline composition as antiparasitic | INTERVET INT BV (NL) | 2023-01-18 | — | — | EP | disclosed |
| CN-114846014-A | Insect repellent compounds comprising azaindole structures | 英特维特国际股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20070238700-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (CH) | 2007-10-11 | — | — | US | disclosed |
| WO-2007079010-A2 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING-PLOUGH LTD. (CH) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | INTERVET INC. | 2007-07-05 | — | — | US | disclosed |
| EP-1799636-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | Schering-Plough Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006135648-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-06-15 | — | — | US | disclosed |
| WO-2006034333-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-03-30 | — | — | WO | disclosed |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH LTD. (CH) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043385-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE | HRH4, PNPO, NME4 | PTGS1 450/4885PTGS2 533/4885CA2 4085/4885 |
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | PNN, AADAC, EPX | PTGS1 460/4885PTGS2 185/4885CA2 2920/4885 |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | CYP4F3, TET1, CYP4F2 | PTGS1 589/4885PTGS2 1206/4885CA2 15/4885 |
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | DHODH, NISCH, DDT | PTGS1 177/4885PTGS2 187/4885CA2 4003/4885 |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | TRHDE, DDT, EPHX1 | PTGS1 1332/4885PTGS2 1406/4885CA2 2220/4885 |
| US-20230148316-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE | DHX35, DDX5, DHODH | PTGS1 806/4885PTGS2 698/4885CA2 4051/4885 |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | PTGS1 296/4885PTGS2 1435/4885CA2 3839/4885 |
| US-20230110397-A1 | ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE | AADAC, HNMT, NISCH | PTGS1 1492/4885PTGS2 1123/4885CA2 4427/4885 |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, TUBA1C | PTGS1 1988/4885PTGS2 1369/4885CA2 651/4885 |
| US-20070238700-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | NAT1, NGLY1, ELANE | PTGS1 243/4885PTGS2 1608/4885CA2 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.