Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729373 | 0.88 | ACHE (0.46) | CYP19A1ACP3NPC1GAAACHE | |
| SCHEMBL1515743 | 0.86 | ACP3 (0.50) | SMN1; SMN2ACP3GAAACHE | |
| SCHEMBL6499767 | 0.84 | CYP3A4 (0.35) | MAPKAPK2CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL6499586 | 0.84 | PSEN1 (0.44) | MAPKAPK2CYP19A1CYP11B1CYP11B2ACP3 | |
| SCHEMBL3903975 | 0.84 | CYP11B1 (0.44) | MAPKAPK2CYP19A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL6504970 | 0.80 | CYP19A1 (0.39) | CYP19A1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3907301 | 0.80 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2KMT2ASMN1; SMN2 | |
| SCHEMBL3403146 | 0.80 | CYP11B1 (0.41) | CYP19A1CYP11B1CYP11B2SLC6A2SLC6A4 | |
| SCHEMBL2145850 | 0.80 | ALDH1A1 (0.39) | KMT2ANPC1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL1515763 | 0.80 | SLC6A3 (0.58) | KMT2AMEN1GAASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | MAPKAPK2 14/4885CYP19A1 2827/4885CYP11B1 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.