SCHEMBL6510153

SCHEMBL6510153

O=C(O)CCN(Cc1cccc(F)c1)Cc1cccc(Cc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
FFAR1 O14842 2/20 0.46
TAS2R14 Q9NYV8 2/20 0.43
FOLH1 Q04609 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
HDAC3 O15379 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
NCOR2 Q9Y618 2/20 0.42
HTT P42858 1/20 0.42
HCAR2 Q8TDS4 2/20 0.41
TP53 P04637 1/20 0.41
RIPK1 Q13546 1/20 0.41
SRC P12931 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6511878 0.95 FFAR1 (0.49) PKMMEN1KMT2AFFAR1TAS2R14
SCHEMBL6511657 0.90 HDAC3 (0.50) MEN1KMT2AL3MBTL1HDAC3HDAC1
SCHEMBL6513938 0.90 PKM (0.44) PKMMEN1KMT2AFFAR1FOLH1
SCHEMBL6510335 0.89 HTT (0.43) PKMMEN1KMT2AFFAR1HDAC3
SCHEMBL6509679 0.86 SMN1; SMN2 (0.45) PKMMEN1KMT2ATAS2R14HDAC3
SCHEMBL6511947 0.85 MTNR1A (0.47) MEN1KMT2AL3MBTL1HDAC3HDAC1
SCHEMBL6512357 0.84 TAS2R14 (0.43) MEN1KMT2ATAS2R14L3MBTL1HDAC3
SCHEMBL6519103 0.84 KMT2A (0.50) MEN1KMT2AFFAR1HDAC3HDAC1
SCHEMBL6511127 0.84 PKM (0.38) PKMMEN1KMT2AFFAR1TAS2R14
SCHEMBL6516556 0.84 LTA4H (0.45) KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed