Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511657 | 0.90 | HDAC3 (0.50) | KMT2AMEN1HTTHDAC3HDAC1 | |
| SCHEMBL6514104 | 0.87 | KMT2A (0.42) | KMT2AMEN1HTTPTGESFFAR1 | |
| SCHEMBL6511947 | 0.85 | MTNR1A (0.47) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL6512357 | 0.84 | TAS2R14 (0.43) | KMT2AMEN1HTTPTGESFFAR4 | |
| SCHEMBL6510153 | 0.84 | PKM (0.47) | KMT2AMEN1HTTFFAR1HDAC3 | |
| SCHEMBL8987604 | 0.83 | KMT2A (0.64) | KMT2AMEN1HTTPTGESFFAR1 | |
| SCHEMBL6531193 | 0.82 | LTA4H (0.46) | FFAR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6511663 | 0.81 | HTT (0.43) | KMT2AMEN1HTTFFAR1HDAC3 | |
| SCHEMBL6515044 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1FFAR1HDAC3HDAC1 | |
| SCHEMBL6509679 | 0.81 | SMN1; SMN2 (0.45) | KMT2AMEN1HTTHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |