Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CTSA | P10619 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510295 | 0.94 | LMNA (0.43) | ITGB1ITGA4LMNACTSAALDH1A1 | |
| SCHEMBL6514009 | 0.71 | ITGB1 (0.58) | ITGB1ITGA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6518236 | 0.71 | ITGB1 (0.52) | ITGB1ITGA4LMNACTSASMN1; SMN2 | |
| SCHEMBL6512467 | 0.71 | ALDH1A1 (0.60) | LMNAALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6512426 | 0.69 | ITGB1 (0.53) | ITGB1ITGA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6515884 | 0.67 | ITGB3 (0.46) | ITGB1ITGA4LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6514203 | 0.66 | ITGB1 (0.49) | ITGB1ITGA4LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6511541 | 0.66 | ITGB1 (0.46) | ITGB1ITGA4CTSAKMT2A | |
| SCHEMBL6509549 | 0.65 | ITGB1 (0.63) | ITGB1ITGA4CTSA | |
| SCHEMBL7569262 | 0.65 | P2RX7 (0.57) | LMNAALDH1A1SMN1; SMN2MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953798-B1 | β-alanine derivates | CELLTECH R&D LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |