Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511657 | 0.86 | HDAC3 (0.50) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL6511861 | 0.85 | CA12 (0.45) | CA12CA1CA2CA4POLB | |
| SCHEMBL6510728 | 0.81 | HDAC1 (0.44) | MEN1KMT2AMAPTLDHALDHB | |
| SCHEMBL6510830 | 0.81 | POLB (0.45) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6511947 | 0.81 | MTNR1A (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6519103 | 0.80 | KMT2A (0.50) | MEN1KMT2AMAPTHDAC1 | |
| SCHEMBL6510153 | 0.80 | PKM (0.47) | MEN1KMT2APKML3MBTL1HDAC1 | |
| SCHEMBL6512357 | 0.80 | TAS2R14 (0.43) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6512519 | 0.79 | POLB (0.50) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6531193 | 0.78 | LTA4H (0.46) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |