Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196680 | 0.90 | MEN1 (0.67) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL22281511 | 0.90 | KMT2A (0.67) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL6218489 | 0.88 | HPGD (0.65) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL6217417 | 0.87 | SMN1; SMN2 (0.64) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL8345028 | 0.82 | MEN1 (0.73) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL6213198 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1MAPTRXFP1 | |
| SCHEMBL6295507 | 0.81 | MEN1 (1.00) | KMT2AMEN1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL6247549 | 0.80 | MAPT (0.57) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL6511873 | 0.79 | HPGD (0.52) | KMT2AMEN1ALDH1A1USP2GAA | |
| SCHEMBL9761035 | 0.79 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | claimed |
| US-20050004126-A1 | Method of determining potential allosterically-binding matrix metalloproteinase inhibitors | ANDRIANJARA CHARLES (FR) | 2005-01-06 | — | — | US | disclosed |
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | KMT2A 3258/4885MEN1 4715/4885ALDH1A1 1357/4885 |
| US-20050004126-A1 | Method of determining potential allosterically-binding matrix metalloproteinase inhibitors | MMP13, MMP12, MMP25 | KMT2A 2962/4885MEN1 1184/4885ALDH1A1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.