Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880267 | 0.80 | ALDH1A1 (0.49) | EGFRALDH1A1MAPK1RXFP1HPGD | |
| SCHEMBL27588037 | 0.76 | RAF1 (0.46) | ALDH1A1LMNAMAPK1RXFP1KDM4E | |
| SCHEMBL22084034 | 0.73 | RAF1 (0.44) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL5154814 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10PDGFRBFLT4 | |
| SCHEMBL27419910 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNACYP2D6MAPK1HPGD | |
| SCHEMBL27405685 | 0.69 | VNN1 (0.53) | ALDH1A1LMNAMAPK1KDM4EHTT | |
| SCHEMBL8000103 | 0.67 | NPC1 (0.56) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22042555 | 0.67 | IRAK4 (0.45) | EGFRALDH1A1LMNARXFP1 | |
| SCHEMBL15234456 | 0.67 | TSHR (0.61) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22732370 | 0.67 | LMNA (0.55) | ALDH1A1LMNACYP3A4CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004126-A1 | Method of determining potential allosterically-binding matrix metalloproteinase inhibitors | ANDRIANJARA CHARLES (FR) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004126-A1 | Method of determining potential allosterically-binding matrix metalloproteinase inhibitors | MMP13, MMP12, MMP25 | EGFR 2563/4885ALDH1A1 4241/4885LMNA 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.