Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420132 | 0.83 | AKT2 (0.42) | AKT2NUDT1GSK3BKITADORA2A | |
| SCHEMBL16513126 | 0.80 | BRAF (0.45) | AKT2GSK3BKIT | |
| SCHEMBL1059581 | 0.75 | NUDT1 (0.68) | AKT2NUDT1ADORA2AADORA1PI4KA | |
| SCHEMBL8009111 | 0.72 | CSF1R (0.71) | CSF1RCYP1A2PI4KAPI4K2BPI4K2A | |
| SCHEMBL9544742 | 0.71 | AKT2 (0.44) | AKT2NUDT1KITADORA2AADORA1 | |
| SCHEMBL3857164 | 0.71 | AKT2 (0.44) | AKT2NUDT1KITADORA2AADORA1 | |
| SCHEMBL8906323 | 0.71 | AKT2 (0.44) | AKT2NUDT1KITADORA2AADORA1 | |
| SCHEMBL1095418 | 0.69 | CYP1A2 (0.60) | CYP1A2HIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL14322494 | 0.68 | PDPK1 (0.38) | PDPK1CYP1A2HIF1ACDK2HTT | |
| SCHEMBL20420131 | 0.68 | YTHDC1 (0.49) | AKT2ADORA1PDPK1CSF1RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912378-B | Hydrazinopurine compounds and triazolopurine compounds for inhibiting xanthine oxidase | 泰拉强石株式会社 | 2023-09-12 | — | — | CN | disclosed |
| US-20050043268-A1 | Inhibition of viruses | MEDICAL RESEARCH COUNCIL (GB) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043268-A1 | Inhibition of viruses | RNASE1, HNRNPA1, RNASEH1 | AKT2 4059/4885NUDT1 277/4885GSK3B 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.