Sugi Predict

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SCHEMBL6515405

SCHEMBL6515405

CCO/C=C(/C(=O)O)c1ccccc1/C(=N\OC(CC)c1ccccn1)OCC1CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTGIR P43119 3/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ CNR2 P34972 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CNR1 P21554 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ TAAR1 Q96RJ0 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3463067 1.00 PTGIR (0.33) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL4623306 0.92 PTGIR (0.34) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL6411933 0.92 PTGIR (0.34) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL4623301 0.92 PTGIR (0.34) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL424400 0.92 CNR2 (0.33) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL424401 0.92 CNR2 (0.33) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL424402 0.84 MEN1 (0.35) PTGIRMEN1GAAKMT2ASMN1; SMN2
SCHEMBL7995297 0.79 ALDH1A1 (0.34) MEN1GAAKMT2ASMN1; SMN2ALDH1A1
SCHEMBL7972362 0.79 ALDH1A1 (0.34) MEN1GAAKMT2ASMN1; SMN2ALDH1A1
SCHEMBL7752753 0.73 MEN1 (0.39) MEN1GAAKMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190178-A1 Pesticidal Treatment Compositions GOWAN COMERCIO INTEMACIONAL E SERVICOS LIMITADA (PT) 2013-07-25 — — US claimed
US-20170245492-A1 AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS RAMOT AT TEL AVIV UNlVERSITY LTD. (IL) 2017-08-31 — — US disclosed
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 — — US disclosed
US-9574109-B2 Surface-modified hydrogels and hydrogel microparticles DOW CORNING CORPORATION (US) 2017-02-21 — — US disclosed
EP-2536786-B1 SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW CORNING (US) 2015-12-30 — — EP disclosed
US-20140073599-A1 Plant Treatment Compositions and Methods for Their Use GOWAN COMERCIO INTERNATIONAL E SERVICOS, LIMITADA (PT) 2014-03-13 — — US disclosed
US-20130184157-A1 Improved Processes for the Control of Undesired Vegetative Growth In Crops Gowan Comercio International E Servicos Limitada (PT) 2013-07-18 — — US disclosed
US-20130172184-A1 Plant Treatment Compositions and Methods for their Use GOWAN COMERCIO INTERNACIONAL E SERVICOS LIMITADA (PT) 2013-07-04 — — US disclosed
US-20120315329-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-12-13 — — US disclosed
US-20120309623-A1 SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW SILICONES CORPORATION 2012-12-06 — — US disclosed
US-6939831-B1 Pestcide and/or plant growth regulating compositions AVENTIS CROPSCIENCE S.A. (FR) 2005-09-06 — — US disclosed
EP-1223807-B1 PESTICIDE AND/OR GROWTH REGULATING COMPOSITIONS WITH PARTICULAR NON-IONIC SURFACTANT BAYER CROPSCIENCE SA (FR) 2003-12-10 — — EP disclosed
EP-1158855-B1 PESTICIDE AND/OR PLANT GROWTH REGULATING COMPOSITIONS BAYER CROPSCIENCE SA (FR) 2003-06-11 — — EP disclosed
EP-1223807-A1 PESTICIDE AND/OR GROWTH REGULATING COMPOSITIONS WITH PARTICULAR NON-IONIC SURFACTANT AVENTIS CROPSCIENCE S.A. (FR) 2002-07-24 — — EP disclosed
WO-2001030147-A1 NOVEL PESTICIDE AND/OR GROWTH REGULATING COMPOSITIONS WITH PARTICULAR NON-IONIC SURFACTANT AVENTIS CROPSCIENCE SA (FR) 2001-05-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190178-A1 Pesticidal Treatment Compositions DDT, CHIT1, CTRL PTGIR 3762/4885MEN1 2994/4885GAA 3242/4885
US-20130184157-A1 Improved Processes for the Control of Undesired Vegetative Growth In Crops AGL, GYS2, GHDC PTGIR 3896/4885MEN1 2958/4885GAA 49/4885
US-20120309623-A1 SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES CD44, EPCAM, ITGAM PTGIR 1135/4885MEN1 2321/4885GAA 2603/4885
US-20130172184-A1 Plant Treatment Compositions and Methods for their Use DDT, AS3MT, IDUA PTGIR 4435/4885MEN1 1815/4885GAA 17/4885
US-20170245492-A1 AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS APEH, JMJD7, AGL PTGIR 4310/4885MEN1 2621/4885GAA 16/4885
US-20120315329-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS PLOD3, CD44, PLOD1 PTGIR 1479/4885MEN1 656/4885GAA 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.