SCHEMBL652142

SCHEMBL652142

Brc1ccc(-c2nc3ccccc3nc2-c2ccc(Br)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.57
KDM4E B2RXH2 3/20 0.57
LMNA P02545 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
GAA P10253 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 3/20 0.52
MAPK14 Q16539 2/20 0.52
MAPK10 P53779 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAPK1 P28482 1/20 0.50
AKT1 P31749 1/20 0.48
AKT2 P31751 1/20 0.48
PKM P14618 1/20 0.48
MAPK13 O15264 1/20 0.47
GCGR P47871 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
CYP1A1 P04798 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31510226 1.00 L3MBTL1 (0.57) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL650086 0.96 L3MBTL1 (0.64) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL30476324 0.96 L3MBTL1 (0.64) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL13071693 0.90 L3MBTL1 (0.48) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL13071764 0.90 TDP1 (0.75) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL23606773 0.88 L3MBTL1 (0.56) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL24036920 0.87 CYP2A6 (0.50) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL28351511 0.86 CYP1A2 (0.54) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL24036921 0.85 L3MBTL1 (0.57) L3MBTL1KDM4ELMNATDP1GAA
SCHEMBL7696463 0.85 NQO2 (0.48) L3MBTL1KDM4ELMNATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10103341-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-10-16 US disclosed
CN-105061514-B Organometallic complex and light-emitting component, light-emitting device and electronic device 株式会社半导体能源研究所 2018-05-08 CN disclosed
US-9429663-B2 Compounds for neutron radiation detectors and systems thereof LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2016-08-30 US disclosed
EP-2067778-B1 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LAB (JP) 2016-08-17 EP disclosed
EP-2067778-B1 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LAB (JP) 2016-08-17 EP disclosed
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
CN-105061514-A Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LAB 2015-11-18 CN disclosed
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-7265378-B2 Electronic devices made with electron transport and/or anti-quenching layers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-09-04 US disclosed
WO-2007032258-A1 QUINOXALINE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-03-22 WO disclosed
WO-2007032258-A1 QUINOXALINE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-03-22 WO disclosed
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-03-15 US disclosed
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-03-15 US disclosed
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-03-15 US disclosed
WO-2006049334-A1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-05-11 WO disclosed
WO-2006022193-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND LIGHTING SYSTEM SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-03-02 WO disclosed
EP-1616864-A1 QUINOXALINE DERIVATIVES, AND ORGANIC SEMICONDUCTOR DEVICES, ELECTROLUMINESCENT DEVICES AND ELECTRONIC APPLIANCES, MADE BY USING THE DERIVATIVES SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-01-18 EP disclosed
US-20050186446-A1 Quinoxaline derivative, and organic semiconductor device, electric field light emitting device, and electronic device which have the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same CRY1, CRY2, ARL1 L3MBTL1 1258/4885KDM4E 347/4885LMNA 3842/4885
US-10103341-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex CRY1, AP1M1, AP2M1 L3MBTL1 169/4885KDM4E 2310/4885LMNA 3469/4885
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative NDUFV2, NDUFS8, NDUFA8 L3MBTL1 1045/4885KDM4E 1813/4885LMNA 2713/4885
US-20050186446-A1 Quinoxaline derivative, and organic semiconductor device, electric field light emitting device, and electronic device which have the same GRK1, GRIA3, RER1 L3MBTL1 2168/4885KDM4E 1642/4885LMNA 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.