Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720537 | 0.77 | TSHR (0.48) | ALDH1A1MAPTGAAGABRA1GABRG2 | |
| SCHEMBL3862889 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL19791860 | 0.75 | TDP1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30413609 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5700377 | 0.75 | GABRA1 (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7985686 | 0.75 | GABRA1 (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL826540 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7697285 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTGABRA1 | |
| SCHEMBL3614808 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL29736537 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195329-B1 | METHOD FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA SAS (FR) | 2013-11-06 | — | — | EP | claimed |
| US-8404804-B2 | Methods and intermediates for chemical synthesis of polypeptides and proteins | IPSEN PHARMA S.A.S. (FR) | 2013-03-26 | — | — | US | claimed |
| US-20100234564-A1 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2010-09-16 | — | — | US | claimed |
| US-20100204449-A1 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2010-08-12 | — | — | US | claimed |
| EP-2197895-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2010-06-23 | — | — | EP | claimed |
| EP-2195329-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2010-06-16 | — | — | EP | claimed |
| WO-2009032181-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2009-03-12 | — | — | WO | claimed |
| WO-2009032133-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2009-03-12 | — | — | WO | claimed |
| US-6875594-B2 | Methods of ligating expressed proteins | THE ROCKEFELLER UNIVERSITY (US) | 2005-04-05 | — | — | US | claimed |
| US-20020151006-A1 | Methods of ligating expressed proteins | MUIR TOM W (US) | 2002-10-17 | — | — | US | claimed |
| EP-0832096-B1 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | SCRIPPS RESEARCH INST (US) | 2001-07-18 | — | — | EP | claimed |
| US-6184344-B1 | Synthesis of proteins by native chemical ligation | THE SCRIPPS RESEARCH INSTITUTE | 2001-02-06 | — | — | US | claimed |
| EP-0832096-A4 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | SCRIPPS RESEARCH INST (US) | 1998-08-05 | — | — | EP | claimed |
| EP-0832096-A1 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | The Scripps Research Institute (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996034878-A1 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-11-07 | — | — | WO | claimed |
| US-11919921-B2 | Galactoside inhibitor of galectins | GALECTO BIOTECH AB (DK) | 2024-03-05 | — | — | US | disclosed |
| US-20220289783-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2022-09-15 | — | — | US | disclosed |
| EP-0832096-A4 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | SCRIPPS RESEARCH INST (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0832096-A1 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | The Scripps Research Institute (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996034878-A1 | SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919921-B2 | Galactoside inhibitor of galectins | LGALS3, LGALS1, LGALS2 | MEN1 2886/4885KMT2A 3585/4885ALDH1A1 1974/4885 |
| US-20220289783-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | LGALS1, LGALS3, LGALS2 | MEN1 3155/4885KMT2A 3920/4885ALDH1A1 1785/4885 |
| US-20100204449-A1 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | PTMS, TMT1A, MTR | MEN1 2187/4885KMT2A 612/4885ALDH1A1 2619/4885 |
| US-20100234564-A1 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | PTMS, RNGTT, MTR | MEN1 1118/4885KMT2A 392/4885ALDH1A1 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.