Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720537 | 0.77 | TSHR (0.48) | ALDH1A1ALOX15TSHRMAPTGAA | |
| SCHEMBL15429537 | 0.76 | NPBWR1 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7375340 | 0.76 | GUCY1B2 (0.50) | ALDH1A1ALOX15MAPTKDM4EMEN1 | |
| SCHEMBL652346 | 0.75 | MEN1 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5700377 | 0.75 | GABRA1 (0.37) | ALDH1A1TSHRMAPTKDM4EMEN1 | |
| SCHEMBL7985686 | 0.75 | GABRA1 (0.37) | ALDH1A1TSHRMAPTKDM4EMEN1 | |
| SCHEMBL3614808 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL19791860 | 0.75 | TDP1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL826540 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTKDM4EMEN1 | |
| SCHEMBL7697285 | 0.75 | ALDH1A1 (0.44) | ALDH1A1ALOX15TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070923-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | JW PHARMACEUTICAL CORP (KR) | 2026-03-12 | — | — | US | disclosed |
| US-12497410-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | JW PHARMACEUTICAL CORPORATION (KR) | 2025-12-16 | — | — | US | disclosed |
| CN-119143779-A | Process for preparing heterocyclic derivative compounds, compositions containing the compounds and hydrates of the compounds | JW 制药公司 | 2024-12-17 | — | — | CN | disclosed |
| EP-3909956-B1 | HYDROCHLORIDE SALT 1.5 HYDRATE OF AN HETEROCYCLIC DERIVATIVE COMPOUND | JW PHARMACEUTICAL CORP (KR) | 2024-12-04 | — | — | EP | disclosed |
| US-12103938-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | JW PHARMACEUTICAL CORPORATION (KR) | 2024-10-01 | — | — | US | disclosed |
| CN-114085235-B | Process for preparing heterocyclic derivative compounds, compositions containing the compounds and hydrates of the compounds | JW 制药公司 | 2024-08-13 | — | — | CN | disclosed |
| US-12030895-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | JW PHARMACEUTICAL CORPORATION (KR) | 2024-07-09 | — | — | US | disclosed |
| US-20240083911-A1 | Method For Preparing Heterocyclic Derivative Compound, Composition Containing Same Compound, And Hydrate of Same Compound | JW PHARMACEUTICAL CORPORATION (KR) | 2024-03-14 | — | — | US | disclosed |
| US-20240067659-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | JW PHARMACEUTICAL CORPORATION (KR) | 2024-02-29 | — | — | US | disclosed |
| US-11866448-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | JW PHARMACEUTICAL CORPORATION (KR) | 2024-01-09 | — | — | US | disclosed |
| US-7504437-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |
| US-7504393-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |
| US-20080255095-A1 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| EP-1362844-B1 | BENZYLAMINE ANALOGUE | BTG INT LTD (GB) | 2007-12-05 | — | — | EP | disclosed |
| US-20070037795-A1 | 2-methyl-1-[2-(4-nitrophenoxy)-ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl dimethylcarbamate; Acetylcholinesterase inhibitors; selective serotonin reuptake inhibitory; Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders | BTG INTERNATIONAL LIMITED (GB) | 2007-02-15 | — | — | US | disclosed |
| US-20070037793-A1 | 2-methyl-1-[2-(4-nitrophenoxy)-ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl dimethylcarbamate; Acetylcholinesterase inhibitors; selective serotonin reuptake inhibitory; Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders | BTG INTERNATIONAL LIMITED (GB) | 2007-02-15 | — | — | US | disclosed |
| US-20040067981-A1 | Acetylcholinesterase inhibitor; Alzheimer's diseases, Hubtington disease, antidepressants | SANKYO COMPANY, LIMITED (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1362844-A1 | BENZYLAMINE ANALOGUE | Sankyo Company, Limited (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-0138983-B1 | N-PHENYL-N'-(PYRIDINYL-N-OXIDE)UREA PLANT REGULATORS | FMC Corporation (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4046896-A | 1-Methyl-2-(pyridyl-oxymethyl)-5-nitro-imidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083911-A1 | Method For Preparing Heterocyclic Derivative Compound, Composition Containing Same Compound, And Hydrate of Same Compound | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-12103938-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-20260070923-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | SLC26A3, SLC10A6, SLC14A1 | ALDH1A1 176/4885ALOX15 612/4885TSHR 2678/4885 |
| US-20070037793-A1 | 2-methyl-1-[2-(4-nitrophenoxy)-ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl dimethylcarbamate; Acetylcholinesterase inhibitors; selective serotonin reuptake inhibitory; Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders | CHRNA4, SLC6A4, DRD4 | ALDH1A1 1070/4885ALOX15 2480/4885TSHR 236/4885 |
| US-20070037795-A1 | 2-methyl-1-[2-(4-nitrophenoxy)-ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl dimethylcarbamate; Acetylcholinesterase inhibitors; selective serotonin reuptake inhibitory; Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders | SLC6A4, SLC6A3, HTR4 | ALDH1A1 1017/4885ALOX15 2260/4885TSHR 147/4885 |
| US-11866448-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-20040067981-A1 | Acetylcholinesterase inhibitor; Alzheimer's diseases, Hubtington disease, antidepressants | ACHE, BACE1, CHRNA6 | ALDH1A1 166/4885ALOX15 2431/4885TSHR 1284/4885 |
| US-20240067659-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-12497410-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-12030895-B2 | Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound | REN, NOD1, NLRP3 | ALDH1A1 1108/4885ALOX15 812/4885TSHR 3151/4885 |
| US-20080255095-A1 | Benzylamine analogues | NR4A3, NAT1, HRH4 | ALDH1A1 1247/4885ALOX15 2505/4885TSHR 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.