Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530119 | 0.86 | S1PR1 (0.44) | PTPN11PTPN1PTPN6 | |
| SCHEMBL6529532 | 0.86 | S1PR1 (0.44) | LTA4HPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6529005 | 0.86 | PTPN11 (0.40) | LTA4HPTPN11CNR2THRATHRB | |
| SCHEMBL6504727 | 0.86 | S1PR1 (0.45) | — | |
| SCHEMBL6527017 | 0.83 | MMP12 (0.40) | — | |
| SCHEMBL6530174 | 0.82 | LMNA (0.39) | PTPN11CNR2THRATHRB | |
| SCHEMBL6530514 | 0.82 | FDFT1 (0.41) | — | |
| SCHEMBL6506648 | 0.82 | PTPN11 (0.40) | LTA4HPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6530992 | 0.81 | LMNA (0.40) | PTPN11 | |
| SCHEMBL6527581 | 0.81 | MMP12 (0.36) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |