Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502328 | 0.83 | RARB (0.42) | PPARGPTGESALOX5PPARARARB | |
| SCHEMBL6529532 | 0.82 | S1PR1 (0.44) | PPARGPTGESALOX5PPARDRARB | |
| SCHEMBL6530119 | 0.82 | S1PR1 (0.44) | PPARGMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6527581 | 0.81 | MMP12 (0.36) | RARBLMNA | |
| SCHEMBL6529230 | 0.81 | LMNA (0.40) | MEN1KMT2ARARBTHRATHRB | |
| SCHEMBL6499997 | 0.79 | LMNA (0.36) | PPARGPTGESALOX5FFAR1LMNA | |
| SCHEMBL6532172 | 0.79 | LTA4H (0.42) | THRATHRBPDE4APDE4BPDE4C | |
| SCHEMBL6529141 | 0.78 | RARB (0.38) | PPARGPTGESALOX5PPARDPPARA | |
| SCHEMBL6529689 | 0.78 | LMNA (0.37) | PPARGPTGESALOX5PPARARARB | |
| SCHEMBL6506648 | 0.77 | PTPN11 (0.40) | SMN1; SMN2THRATHRBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |