Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529230 | 0.87 | LMNA (0.40) | RARBLMNACNR2 | |
| SCHEMBL6529532 | 0.86 | S1PR1 (0.44) | RARBRARAFFAR1S1PR1PTGES | |
| SCHEMBL6529689 | 0.86 | LMNA (0.37) | RARBRARALMNAFFAR1PTGES | |
| SCHEMBL6530992 | 0.84 | LMNA (0.40) | RARBLMNAPTGESALOX5PPARG | |
| SCHEMBL6528235 | 0.83 | S1PR1 (0.46) | RARBRARALMNACNR2FFAR1 | |
| SCHEMBL6530514 | 0.83 | FDFT1 (0.41) | LMNAPTGESALOX5PPARG | |
| SCHEMBL6529753 | 0.83 | PPARG (0.34) | RARBLMNAFFAR1FFAR4PTGES | |
| SCHEMBL6529916 | 0.80 | CYP2D6 (0.39) | PTGESALOX5PPARGPPARA | |
| SCHEMBL6530119 | 0.79 | S1PR1 (0.44) | LMNAS1PR1PPARG | |
| SCHEMBL6529141 | 0.79 | RARB (0.38) | RARBLMNAFFAR1FFAR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |