Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL809681 | 0.97 | CYP2C19 (0.41) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL6049892 | 0.83 | CYP2C19 (0.46) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL28118925 | 0.70 | GAA (0.46) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL28617832 | 0.69 | CYP2C19 (0.54) | CYP2C19GAAMAPTMEN1KMT2A | |
| Zinc Ion SCHEMBL629245 | 0.68 | GAA (0.42) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL1668654 | 0.68 | POLB (0.35) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL11341714 | 0.68 | GAA (0.41) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL28414862 | 0.68 | KMT2A (0.50) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL10901866 | 0.67 | MEN1 (0.45) | CYP2C19GAAMAPTMEN1KMT2A | |
| SCHEMBL10431646 | 0.67 | GAA (0.43) | CYP2C19GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039733-A1 | METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | Arkema, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |
| EP-2970605-B1 | METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | ARKEMA INC (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3230356-B1 | COMPOSITIONS AND METHODS FOR CROSSLINKING POLYMERS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | ARKEMA INC (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10563039-B2 | Compositions and methods for crosslinking polymers in the presence of atmospheric oxygen | ARKEMA INC. (US) | 2020-02-18 | — | — | US | disclosed |
| CN-107001685-B | Composition and method for crosslinking polymers in the presence of atmospheric oxygen | 阿科玛股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| EP-3230356-A1 | COMPOSITIONS AND METHODS FOR CROSSLINKING POLYMERS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | Arkema, Inc. (US) | 2017-10-18 | — | — | EP | disclosed |
| US-20170267832-A1 | COMPOSITIONS AND METHODS FOR CROSSLINKING POLYMERS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | ARKEMA INC. | 2017-09-21 | — | — | US | disclosed |
| CN-105189619-B | Method for crosslinking polymer compositions in the presence of atmospheric oxygen | 阿科玛股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-107001685-A | Composition and method for crosslinking polymers in the presence of atmospheric oxygen | 阿科玛股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| US-9644089-B2 | Methods for crosslinking polymer compositions in the presence of atmospheric oxygen | ARKEMA INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160017135-A1 | METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | ARKEMA INC. | 2016-01-21 | — | — | US | disclosed |
| EP-2970605-A1 | METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | Arkema, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-105189619-A | Method for crosslinking polymer compositions in the presence of atmospheric oxygen | ARKEMA INC | 2015-12-23 | — | — | CN | disclosed |
| WO-2014158665-A1 | METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN | ARKEMA INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20040180985-A1 | Tack free surface cures of polymers by organic peroxides in the presence of air | ARKEMA INC. | 2004-09-16 | — | — | US | disclosed |
| US-6747099-B1 | BIS-, TRI- AND HIGHER POLY-MALEIMIDES, SILICONE ELASTOMER, P-PHENYLENEDIAMINE BASED ANTIOZONANTS, SULFUR VULCANIZATION ACCELERANT | ATOFINA CHEMICALS, INC. | 2004-06-08 | — | — | US | disclosed |
| EP-1149122-A4 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | ATOFINA CHEM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| CN-1336939-A | Tack-free surface curing of polymers by organic peroxides in the presence of air | ATOFINA CHEM INC (US) | 2002-02-20 | — | — | CN | disclosed |
| EP-1149122-A1 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | Atofina Chemicals, Inc. (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2001034680-A1 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | ATOFINA CHEMICALS, INC. (US) | 2001-05-17 | — | — | WO | disclosed |