Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243182 | 0.88 | AURKA (0.41) | CTSKMAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6679019 | 0.85 | HDAC4 (0.39) | CTSSCTSKMAPTGRIN2DGRIN3B | |
| SCHEMBL6676274 | 0.81 | CA2 (0.41) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6547633 | 0.81 | BACE1 (0.42) | PPARGBACE1CTSSCTSKMAPT | |
| SCHEMBL6676280 | 0.79 | GRIN2D (0.39) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6689704 | 0.77 | RXFP1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6679740 | 0.76 | AURKA (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11573224 | 0.75 | CTSK (0.46) | PPARGBACE1CTSSCTSKMAPT | |
| SCHEMBL6686317 | 0.75 | ITGB3 (0.49) | PPARGCTSSCTSKMAPTKDM4E | |
| SCHEMBL6680723 | 0.75 | CYP3A4 (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142317-A1 | Use of amino acid transporter atbo,+ as a delivery system for drugs and prodrugs | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | US | claimed |
| US-20040142317-A1 | Use of amino acid transporter atbo,+ as a delivery system for drugs and prodrugs | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1384081-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | Medical College Of Georgia Research Institute, Inc. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002083060-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |