Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401236 | 0.77 | CA2 (0.50) | TSHRHDAC1HDAC2ALDH1A1SLC6A3 | |
| SCHEMBL6539103 | 0.76 | MAPT (0.55) | — | |
| SCHEMBL5834996 | 0.75 | — | — | |
| SCHEMBL15710827 | 0.75 | CPB2 (0.54) | CPB2GSRRNPEPGABRR1LMNA | |
| SCHEMBL970515 | 0.74 | MAPT (0.59) | BLM | |
| SCHEMBL527476 | 0.74 | MAPT (0.59) | BLM | |
| SCHEMBL10923278 | 0.74 | MAPT (0.59) | BLM | |
| SCHEMBL10727967 | 0.74 | GSR (0.42) | CPB2GSRRNPEPLMNATHRB | |
| SCHEMBL19124775 | 0.72 | PAOX (0.43) | CPB2GSRRNPEPLMNATHRB | |
| SCHEMBL21980323 | 0.72 | PAOX (0.43) | CPB2GSRRNPEPLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040181056-A1 | Process for preparing cephalosporanic acid derivatives using a-ketoacid derivatives | BIOFERMA MURCIA S.A. | 2004-09-16 | — | — | US | disclosed |
| US-20040175783-A1 | Process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives | BIOFERMA MURCIA S.A. | 2004-09-09 | — | — | US | disclosed |
| US-6730497-B2 | ENZYMATICALLY CONVERTING A 3-THIOLATED CEPHALOSPORIN C INTO A 3-THIOLATED-ALPHA-KETOADIPYL-7-AMINOCEPHALOSPORANIC ACID DERIVATIVE OF USE IN THE PREPARATION OF CEPHALOSPORIN C ANTIBIOTICS AND DERIVATIVES THEREOF | BIOFERMA MURCIA S.A. (ES) | 2004-05-04 | — | — | US | disclosed |
| US-20040067549-A1 | Process for preparing cephalosporin derivatives | BIOFERMA MURCIA S.A. | 2004-04-08 | — | — | US | disclosed |
| EP-1381690-A2 | ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES | Bioferma Murcia, S.A. (ES) | 2004-01-21 | — | — | EP | disclosed |
| EP-1379531-A2 | ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORANIC ACID DERIVATIVES USING ALPHA-KETOACID DERIVATIVES | Bioferma Murcia, S.A. (ES) | 2004-01-14 | — | — | EP | disclosed |
| US-6642020-B2 | Enzymatically converting a 3-thiolated cephalosporin C compound to form a 3-thiolated -glutaryl-7-amino cephalosporanic acid compound; enzymatically converting to form 3-thiolated-7-amino cephalosporanic acid compound | BIOFERMA MURCIA S.A. (ES) | 2003-11-04 | — | — | US | disclosed |
| US-20030104515-A1 | Enzymatically converting a 3-thiolated cephalosporin C into a 3-thiolated-alpha-ketoadipyl-7-aminocephalosporanic acid derivative of use in the preparation of cephalosporin C antibiotics and derivatives thereof | BIOFERMA MURCIA S.A. (ES) | 2003-06-05 | — | — | US | disclosed |
| US-20030073156-A1 | Process for preparing cephalosporin derivatives | BIOFERMA MURCIA S.A. (ES) | 2003-04-17 | — | — | US | disclosed |
| WO-2002086143-A2 | ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES | BIOFERMA MURCIA, S.A. (ES) | 2002-10-31 | — | — | WO | disclosed |
| EP-0517200-B1 | Process for the enzymatic production of cephalosporane derivatives | MINI RICERCA SCIENT TECNOLOG (IT) | 1996-08-14 | — | — | EP | disclosed |
| US-5296358-A | Oxidative deamination | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-03-22 | — | — | US | disclosed |
| EP-0517200-A2 | Process for the enzymatic production of cephalosporane derivatives | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1992-12-09 | — | — | EP | disclosed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4281116-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030104515-A1 | Enzymatically converting a 3-thiolated cephalosporin C into a 3-thiolated-alpha-ketoadipyl-7-aminocephalosporanic acid derivative of use in the preparation of cephalosporin C antibiotics and derivatives thereof | ALDH7A1, DDC, KYAT3 | CPB2 250/4885GSR 3338/4885RNPEP 48/4885 |
| US-20040175783-A1 | Process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives | ALDH7A1, BCKDK, CYP3A7 | CPB2 647/4885GSR 3204/4885RNPEP 287/4885 |
| US-20040181056-A1 | Process for preparing cephalosporanic acid derivatives using a-ketoacid derivatives | ALDH7A1, BCKDK, CYP3A7 | CPB2 661/4885GSR 3297/4885RNPEP 240/4885 |
| US-20030073156-A1 | Process for preparing cephalosporin derivatives | ALDH7A1, COASY, AADAC | CPB2 356/4885GSR 1180/4885RNPEP 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.