SCHEMBL6552405

SCHEMBL6552405

O=S(=O)(Oc1ccc(C23CC4CC(CC(C4)C2)C3)cc1)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
RAB9A P51151 1/20 0.48
LMNA P02545 3/20 0.47
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 1/20 0.41
HIF1A Q16665 6/20 0.40
EPAS1 Q99814 3/20 0.40
EPHX2 P34913 2/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
CASP2 P42575 1/20 0.39
STS P08842 1/20 0.38
ENPP3 O14638 1/20 0.38
CA2 P00918 1/20 0.38
ENPP1 P22413 1/20 0.38
ENPP2 Q13822 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601663 0.94 MEN1 (0.40) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL27573586 0.93 MEN1 (0.46) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL19089846 0.91 PGR (0.42) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL6202886 0.87 LMNA (0.38) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL23040803 0.84 MEN1 (0.36) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL14120878 0.83 LMNA (0.44) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL2611715 0.83 MEN1 (0.45) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL19149745 0.81 MEN1 (0.54) MEN1KMT2ARAB9ALMNAALDH1A1
Potassium Ion SCHEMBL31649385 0.81 MEN1 (0.50) MEN1KMT2ARAB9ALMNAALDH1A1
Adamantane SCHEMBL28719949 0.76 CA2 (0.45) MEN1KMT2ALMNAENPP3CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720037-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 16380026 Canada Inc. (CA) 2026-04-08 EP disclosed
US-20250160195-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2025-05-15 US disclosed
CN-119954851-A Light-emitting device, electronic apparatus, electronic device, and heterocyclic compound 三星显示有限公司 2025-05-09 CN disclosed
WO-2025057775-A1 MATERIAL FOR PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT, AND IMAGING ELEMENT 東ソー株式会社 2025-03-20 WO disclosed
US-20240164208-A1 ORGANIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-16 US disclosed
CN-111825558-B Novel compound and organic light-emitting device 乐金显示有限公司 2024-05-03 CN disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-20230157155-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
EP-1117628-B1 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS ALLERGAN INC (US) 2003-11-19 EP disclosed
EP-1192122-B1 BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI SYNTHELABO (FR) 2003-10-22 EP disclosed
US-6482986-B1 Benzene derivatives, preparation method and pharmaceutical compositions containing same SANOFI-SYNTHELABO (FR) 2002-11-19 US disclosed
US-6403638-B1 COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME ALLERGAN SALES, INC. 2002-06-11 US disclosed
EP-1192122-A1 BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI-SYNTHELABO (FR) 2002-04-03 EP disclosed
WO-2001070662-A2 2,4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS ALLERGAN , INC. (US) 2001-09-27 WO disclosed
EP-1117628-A1 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS Allergan Sales, Inc. (US) 2001-07-25 EP disclosed
WO-2000076953-A1 BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI-SYNTHELABO (FR) 2000-12-21 WO disclosed
US-6147224-A 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors ALLERGAN SALES, INC. (US) 2000-11-14 US disclosed
WO-2000020370-A1 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS ALLERGAN SALES, INC. (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844270-B2 Compound and organic light emitting device including the same TMEM109, CRY1, VDAC1 MEN1 1603/4885KMT2A 2450/4885RAB9A 1147/4885
US-20240164208-A1 ORGANIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME OR10J3, LEF1, L1CAM MEN1 1358/4885KMT2A 1780/4885RAB9A 2469/4885
US-20230157155-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE CRY1, SLC1A2, CHRM1 MEN1 463/4885KMT2A 381/4885RAB9A 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.