Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557145 | 0.80 | CYP2A6 (0.34) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6790824 | 0.76 | BACE1 (0.42) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL15452354 | 0.68 | RAB9A (0.39) | NPC1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL16076484 | 0.68 | KDM4E (0.36) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL16708592 | 0.66 | ALDH1A1 (0.49) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6559396 | 0.65 | PNLIP (0.43) | KMT2AALDH1A1MEN1MAPTCYP3A4 | |
| SCHEMBL13180056 | 0.64 | CYP19A1 (0.43) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL20845357 | 0.64 | CYP1A1 (0.36) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL13567721 | 0.64 | PDE10A (0.34) | NPC1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL38924 | 0.63 | ALDH1A1 (0.56) | NPC1KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | claimed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | claimed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | claimed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | disclosed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | disclosed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | TYR, MPO, NISCH | NPC1 524/4885KMT2A 2803/4885ALDH1A1 646/4885 |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | NPC1 4709/4885KMT2A 1669/4885ALDH1A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.