Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452354 | 0.86 | RAB9A (0.39) | ALDH1A1MAPTKDM4EKMT2AHSD17B10 | |
| SCHEMBL12230342 | 0.83 | MAPT (0.38) | MAPTMEN1KMT2ANPSR1RAB9A | |
| SCHEMBL14684667 | 0.82 | NR1H4 (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6555925 | 0.80 | NPC1 (0.37) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6555659 | 0.80 | ALOX5 (0.44) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6790824 | 0.78 | BACE1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6557114 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL16708592 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10044913 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL16520790 | 0.73 | MAPT (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | claimed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | claimed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | claimed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| US-9526769-B2 | Macrocylic oximyl hepatitis C protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-8940688-B2 | Fluorinated tripeptide HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2015-01-27 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| US-8268776-B2 | mixture of cytochrome P450 monooxygenase inhibitor and protease inhibitor for anti-hepatitis C viral treatment; including other active drugs as interferon, ribavarin, and adamantine | ENANTA PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090197888-A1 | FLUORINATED TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2009-08-06 | — | — | US | disclosed |
| WO-2009076173-A2 | FLUORINATED TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | disclosed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | disclosed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | TYR, MPO, NISCH | CYP2A6 559/4885ALDH1A1 646/4885MAPT 3703/4885 |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | CYP2A6 365/4885ALDH1A1 9/4885MAPT 1389/4885 |
| US-20090197888-A1 | FLUORINATED TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS | CTSC, PRSS1, SPINT2 | CYP2A6 1369/4885ALDH1A1 1805/4885MAPT 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.