Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557887 | 0.87 | HTR7 (0.51) | HTR7HSD17B10PDE10A | |
| SCHEMBL6555790 | 0.86 | MEN1 (0.52) | ACHEHTR7HSD17B10PDE10A | |
| SCHEMBL6557412 | 0.84 | PDE10A (0.57) | HTR7PDE10A | |
| SCHEMBL6555842 | 0.80 | TSHR (0.52) | HTR7HSD17B10 | |
| SCHEMBL6555584 | 0.79 | PDE4A (0.50) | HSD17B10 | |
| SCHEMBL6555791 | 0.76 | PPARA (0.49) | — | |
| SCHEMBL6557882 | 0.75 | KDM4E (0.44) | — | |
| SCHEMBL6557586 | 0.74 | KDM4E (0.52) | HSD17B10PDE10A | |
| SCHEMBL6557988 | 0.74 | L3MBTL1 (0.51) | HSD17B10 | |
| SCHEMBL6556016 | 0.74 | L3MBTL1 (0.51) | HSD17B10PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | disclosed |