Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560446 | 0.88 | CTSS (0.36) | KMT2A | |
| SCHEMBL6559638 | 0.86 | ELANE (0.34) | — | |
| SCHEMBL6559309 | 0.82 | SMN1; SMN2 (0.35) | HPGDTP53 | |
| SCHEMBL6560414 | 0.82 | PSMB5 (0.32) | — | |
| SCHEMBL6559677 | 0.81 | FAAH (0.34) | FAAH | |
| SCHEMBL6559652 | 0.72 | PDF (0.32) | — | |
| SCHEMBL6559238 | 0.71 | MMP1 (0.36) | — | |
| SCHEMBL6558487 | 0.71 | PDF (0.32) | — | |
| SCHEMBL6558834 | 0.71 | MMP2 (0.43) | — | |
| SCHEMBL6558471 | 0.71 | CTSB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |