Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | RRM1 | P23921 | 3/20 | 0.32 |
| ▸ | RRM2 | P31350 | 3/20 | 0.32 |
| ▸ | RRM2B | Q7LG56 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559238 | 0.90 | MMP1 (0.36) | PDFRRM1RRM2RRM2BMMP1 | |
| SCHEMBL6558487 | 0.85 | PDF (0.32) | PDFRRM1RRM2RRM2BMMP1 | |
| SCHEMBL6559675 | 0.84 | PDF (0.31) | PDFRRM1RRM2RRM2BMMP1 | |
| SCHEMBL6558834 | 0.81 | MMP2 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6558471 | 0.81 | CTSB (0.49) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL6558814 | 0.80 | MMP2 (0.45) | MMP2MMP3 | |
| SCHEMBL6558964 | 0.76 | MMP3 (0.41) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL6558829 | 0.75 | MMP1 (0.32) | PDFRRM1RRM2RRM2BMMP1 | |
| SCHEMBL6558880 | 0.75 | REN (0.32) | — | |
| SCHEMBL6558744 | 0.74 | RRM1 (0.30) | RRM1RRM2RRM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |