Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 7/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.38 |
| ▸ | PSMD11 | O00231 | 2/20 | 0.38 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.38 |
| ▸ | PSMD3 | O43242 | 2/20 | 0.38 |
| ▸ | PSMC3 | P17980 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558471 | 0.88 | CTSB (0.49) | MMP3MMP1MMP8PSMB5CTSB | |
| SCHEMBL6558834 | 0.81 | MMP2 (0.43) | MMP3MMP1MMP9MMP2MMP14 | |
| SCHEMBL6558814 | 0.80 | MMP2 (0.45) | MMP3MMP2 | |
| SCHEMBL6559238 | 0.79 | MMP1 (0.36) | MMP3MMP1MMP8MMP9MMP2 | |
| SCHEMBL6558798 | 0.76 | CTSB (0.39) | MMP8PSMB5CTSBREN | |
| SCHEMBL6559652 | 0.76 | PDF (0.32) | MMP3MMP1MMP8MMP9MMP2 | |
| SCHEMBL6558487 | 0.71 | PDF (0.32) | MMP3MMP1MMP8MMP9MMP2 | |
| SCHEMBL6560446 | 0.70 | CTSS (0.36) | CTSB | |
| SCHEMBL6559675 | 0.70 | PDF (0.31) | MMP3MMP1MMP8MMP9REN | |
| SCHEMBL6559638 | 0.67 | ELANE (0.34) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |