Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558471 | 0.86 | CTSB (0.49) | CTSBMMP8NFKB1PSMB5NFKB2 | |
| SCHEMBL6558487 | 0.83 | PDF (0.32) | MMP8MMP13 | |
| SCHEMBL6559675 | 0.79 | PDF (0.31) | MMP8RENMMP13 | |
| SCHEMBL6558834 | 0.77 | MMP2 (0.43) | MMP13 | |
| SCHEMBL6558964 | 0.76 | MMP3 (0.41) | CTSBMMP8PSMB5REN | |
| SCHEMBL6558814 | 0.75 | MMP2 (0.45) | — | |
| SCHEMBL6558829 | 0.74 | MMP1 (0.32) | MMP8MMP13 | |
| SCHEMBL6559652 | 0.74 | PDF (0.32) | MMP8MMP13 | |
| SCHEMBL6559238 | 0.73 | MMP1 (0.36) | MMP8MMP13 | |
| SCHEMBL6558836 | 0.73 | MMP13 (0.37) | HTRA1PSMB5MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |