Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560855 | 0.96 | RIPK1 (0.49) | RIPK1MAOBDRD4DRD2DRD3 | |
| SCHEMBL27341297 | 0.76 | PRMT5 (0.49) | RIPK1PRMT5WDR77GRM5ADAM17 | |
| SCHEMBL14948763 | 0.70 | CHRNB2 (0.59) | MAOBDRD4DRD2DRD3MAPT | |
| SCHEMBL6560000 | 0.70 | PRMT5 (0.40) | RIPK1PRMT5WDR77MAOBDRD4 | |
| SCHEMBL878861 | 0.69 | NPSR1 (0.56) | RIPK1GRM5NPSR1SCD5MAPT | |
| SCHEMBL19501003 | 0.68 | RIPK1 (0.62) | RIPK1DRD4DRD2DRD3ADAM17 | |
| SCHEMBL24775063 | 0.68 | DRD2 (0.46) | RIPK1MAOBDRD4DRD2DRD3 | |
| SCHEMBL18609682 | 0.68 | RIPK1 (0.46) | RIPK1GRM5SCD5 | |
| SCHEMBL12677862 | 0.67 | OPRK1 (0.49) | RIPK1MAOBDRD4DRD2DRD3 | |
| SCHEMBL3942005 | 0.67 | TRPA1 (0.64) | TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | disclosed |