Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562125 | 0.93 | LMNA (0.60) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL6563618 | 0.91 | ALDH1A1 (0.53) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL6561650 | 0.89 | KEAP1 (0.53) | RAB9ANPC1LMNASMN1; SMN2TSHR | |
| SCHEMBL6563639 | 0.88 | MEN1 (0.47) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL6562093 | 0.84 | SMN1; SMN2 (0.54) | RAB9ANPC1LMNASMN1; SMN2KMT2A | |
| SCHEMBL19402549 | 0.79 | CSF1R (0.69) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL6415832 | 0.76 | RAB9A (0.72) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL6561743 | 0.75 | LMNA (0.53) | NPC1LMNASMN1; SMN2KMT2AHTT | |
| SCHEMBL29625262 | 0.73 | SMN1; SMN2 (0.61) | RAB9ANPC1CSF1RLMNASMN1; SMN2 | |
| SCHEMBL19034 | 0.73 | SMN1; SMN2 (0.61) | RAB9ANPC1CSF1RLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990645-B1 | NOVEL SULFONAMIDE DERIVATIVES | NIPPON KAYAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6180796-B1 | TUBULIN POLYMERIZATION INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-01-30 | — | — | US | disclosed |