Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRB | P24530 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562125 | 0.88 | LMNA (0.60) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL6561793 | 0.88 | RAB9A (0.51) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL6563618 | 0.86 | ALDH1A1 (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL6561650 | 0.84 | KEAP1 (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL6562093 | 0.80 | SMN1; SMN2 (0.54) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL9564642 | 0.78 | RAB9A (0.62) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL19402543 | 0.77 | KMT2A (0.67) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL19376893 | 0.77 | RAB9A (0.59) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL18341046 | 0.74 | KDM4E (0.63) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL21987781 | 0.73 | LMNA (0.61) | MEN1KMT2ALMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990645-B1 | NOVEL SULFONAMIDE DERIVATIVES | NIPPON KAYAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6180796-B1 | TUBULIN POLYMERIZATION INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0990645-A1 | NOVEL SULFONAMIDE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-05 | — | — | EP | disclosed |