Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674981 | 0.91 | ABL1 (0.43) | HPGDNAMPTABL1RIN1PTPN11 | |
| SCHEMBL7686729 | 0.91 | PTPN11 (0.43) | GRM5HPGDNAMPTABL1RIN1 | |
| SCHEMBL6565384 | 0.89 | GRM5 (0.46) | GRM5HPGDNAMPTABL1RIN1 | |
| SCHEMBL6563002 | 0.86 | HRH3 (0.42) | GRM5HPGDNAMPTPTPN11HRH3 | |
| SCHEMBL6563511 | 0.83 | PTPN11 (0.40) | PTPN11GRM3POLBHSD11B1 | |
| SCHEMBL6563920 | 0.82 | KLK5 (0.41) | PTPN11KMT2AALDH1A1 | |
| SCHEMBL6565248 | 0.82 | GRM5 (0.56) | GRM5HPGDHRH3CRHBPCRHR2 | |
| SCHEMBL6565533 | 0.81 | ACACB (0.45) | ABL1RIN1PTPN11KMT2AALDH1A1 | |
| SCHEMBL6561810 | 0.80 | HSD11B1 (0.40) | ABL1RIN1PTPN11ACHEALDH1A1 | |
| SCHEMBL6565229 | 0.79 | PTPN11 (0.34) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |