Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674981 | 0.93 | ABL1 (0.43) | ACACBPTPN11HPGDNAMPTPOLB | |
| SCHEMBL7686729 | 0.93 | PTPN11 (0.43) | GRM5ACACBPTPN11HPGDNAMPT | |
| SCHEMBL6561858 | 0.89 | GRM5 (0.47) | GRM5PTPN11HPGDNAMPTPOLB | |
| SCHEMBL6565322 | 0.83 | RAB9A (0.46) | HPGDNPC1NAMPTPOLBMEN1 | |
| SCHEMBL6563002 | 0.82 | HRH3 (0.42) | GRM5PTPN11HPGDNPC1NAMPT | |
| SCHEMBL6565533 | 0.82 | ACACB (0.45) | ACACBPTPN11MEN1KMT2AABL1 | |
| SCHEMBL6561810 | 0.81 | HSD11B1 (0.40) | ACACBPTPN11EGLN1ABL1RIN1 | |
| SCHEMBL7676583 | 0.81 | GRM5 (0.54) | GRM5ACACBHPGDALOX15EPHX2 | |
| SCHEMBL6563070 | 0.81 | PTPN11 (0.44) | PTPN11NAMPTMEN1KMT2A | |
| SCHEMBL6563511 | 0.81 | PTPN11 (0.40) | PTPN11NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |