Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564996 | 0.91 | KMT2A (0.54) | KMT2AGRM4ALDH1A1MAPTHPGD | |
| SCHEMBL7670696 | 0.87 | KMT2A (0.44) | KMT2AKDM4EPKMNPC1MITF | |
| SCHEMBL6563532 | 0.84 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL6565480 | 0.79 | GSK3B (0.47) | ALDH1A1SMN1; SMN2VNN1 | |
| SCHEMBL6563651 | 0.79 | MAPK13 (0.45) | KMT2AALDH1A1HTTMEN1NPC1 | |
| SCHEMBL6565285 | 0.79 | NPC1 (0.49) | ALDH1A1MAPTNPC1RAB9AEGLN1 | |
| SCHEMBL6562338 | 0.78 | GAA (0.47) | KMT2AALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL6565408 | 0.77 | CNR1 (0.41) | KMT2AALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL7677085 | 0.76 | VNN1 (0.46) | EGLN1PTGDR2GRM5VNN1 | |
| SCHEMBL6561875 | 0.76 | HPGD (0.47) | KMT2AALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |