Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563213 | 0.88 | KMT2A (0.39) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL6563532 | 0.86 | ALDH1A1 (0.44) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL7675063 | 0.86 | F2 (0.48) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL6565408 | 0.86 | CNR1 (0.41) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6565480 | 0.84 | GSK3B (0.47) | ALDH1A1SMN1; SMN2SAE1UBA2GSK3A | |
| SCHEMBL14454220 | 0.83 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL31186049 | 0.83 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL6565441 | 0.79 | KMT2A (0.46) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6563737 | 0.79 | EGLN1 (0.45) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL6564223 | 0.78 | VNN1 (0.41) | MAPK13MAPK12MAPK11MAPK14PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |