Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6562640

CCCOC(=O)OC1CC[S+](c2ccccc2)C1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLNR O43193 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HRH1 P35367 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
OPRK1 P41145 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KCNH2 Q12809 1/20 0.33
CACNA1C Q13936 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C19 P33261 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP14 P50281 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6564000 0.94 POLB (0.34) CHRM2CHRM1CHRM3KCNH2CYP2C19
Trifluoromethanesulfonic Acid SCHEMBL6564531 0.92 KMT2A (0.33) CYP2C19SMN1; SMN2ALDH1A1MAPT
SCHEMBL7866635 0.89 LMNA (0.40) MLNRCHRM2CHRM1CHRM3HTR2A
Trifluoromethanesulfonic Acid SCHEMBL6564518 0.86 RORC (0.33) CYP2C19MAPT
Trifluoromethanesulfonic Acid SCHEMBL6564008 0.86 KCNH2 (0.33) MLNRCHRM2CHRM1CHRM3HTR2A
Trifluoromethanesulfonic Acid SCHEMBL3367466 0.85 ALDH1A1 (0.32) ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL6562721 0.84 STS (0.30)
Trifluoromethanesulfonic Acid SCHEMBL6562885 0.83 CYP2C19 (0.31) CYP2C19
Trifluoromethanesulfonic Acid SCHEMBL6564774 0.80 HSD11B1 (0.34) DRD3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL3365764 0.80 CNR1 (0.32) KCNH2GAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed