Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.56 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.56 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.56 |
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913638 | 0.97 | ALDH1A1 (0.65) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6915856 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6917664 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL8720142 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| Zinc Ion SCHEMBL6908105 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6917676 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL8714704 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6915327 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6908824 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL1655868 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873135-B | Polyanionic cellulose, and preparation method and application thereof | 中石化南京化工研究院有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117447691-A | Polyether defoamer for oil field and preparation method thereof | 东营施普瑞石油工程技术有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116426015-A | Aromatic side chain type fluorine-free polyfluorene ether ketone proton exchange membrane and preparation method thereof | 福州大学 | 2023-07-14 | — | — | CN | claimed |
| CN-116375907-A | Method for producing sugammadex | 默沙东有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| CN-115873135-A | Polyanionic cellulose and preparation method and application thereof | 中石化南京化工研究院有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-112010723-B | Method for preparing diaryl methyl substituted thioether | 湖南理工学院 | 2022-08-19 | — | — | CN | claimed |
| CN-111234818-B | Method for synthesizing surface functional group modified carbon quantum dots and application of carbon quantum dots in nano oil displacement | 西南石油大学 | 2022-03-18 | — | — | CN | claimed |
| US-20210206884-A1 | PROCESSES FOR THE PREPARATION OF SUGAMMADEX | MERCK SHARP & DOHME CORP. (US) | 2021-07-08 | — | — | US | claimed |
| EP-3802627-A1 | PROCESSES FOR THE PREPARATION OF SUGAMMADEX | Merck Sharp & Dohme Corp. (US) | 2021-04-14 | — | — | EP | claimed |
| CN-112449642-A | Process for preparing sugammadex | 默沙东公司 | 2021-03-05 | — | — | CN | claimed |
| CN-105622691-A | Synthetic method of 1,6-anhydrocellobiose | CHAOYANG KANGQUAN MEDICAL TECH CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-103388181-A | Terahertz non-linear optical crystal 4-[4-(dimethylamino)styryl]-methylpyridine . p-toluenesulfonate | FUJIAN MATTER STRUCTURE | 2013-11-13 | — | — | CN | claimed |
| CN-102351749-B | Benzenesulphonate anionic gemini surfactant and preparation method thereof | BENGBU BBCA MEDICINE SCIENCE DEV CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-102020836-B | Microcapsule fire retardant for makrolon and preparation method and application thereof | GUANGZHOU SHINE POLYMER TECHNOLOGY CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-102351851-A | 4-(5-dimethylaminothiophenevinyl)methylpyridine sulfonate, second-order nonlinear optical crystal of 4-(5-dimethylaminothiophenevinyl)methylpyridine sulfonate, and their preparation methods | UNIV BEIJING SCIENCE & TECH | 2012-02-15 | — | — | CN | claimed |
| CN-102351749-A | Benzenesulphonate anionic gemini surfactant and preparation method thereof | BENGBU BBCA MEDICINE SCIENCE DEV CO LTD | 2012-02-15 | — | — | CN | claimed |
| CN-102020836-A | Microcapsule fire retardant for makrolon and preparation method and application thereof | GUANGZHOU SHINE POLYMER TECHNOLOGY CO LTD | 2011-04-20 | — | — | CN | claimed |
| EP-0400657-B1 | Process for developing of ps plates requiring no dampening water | FUJI PHOTO FILM CO LTD (JP) | 1996-03-27 | — | — | EP | claimed |
| US-5290665-A | Process for developing PS plate requiring no dampening water wherein the developer comprises, water, a solubilizer and an ethylene glycol mono(alkyl C6 -C8) ether derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| EP-0400657-A2 | Process for developing of ps plates requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1990-12-05 | — | — | EP | claimed |