Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570156 | 0.87 | SIGMAR1 (0.43) | SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6570120 | 0.86 | L3MBTL1 (0.47) | SIGMAR1ACHEALDH1A1USP2GAA | |
| SCHEMBL5713440 | 0.75 | SIGMAR1 (0.50) | SIGMAR1ACHEALDH1A1USP2GAA | |
| SCHEMBL13504052 | 0.70 | SIGMAR1 (0.88) | SIGMAR1ACHEALDH1A1USP2 | |
| SCHEMBL6569758 | 0.69 | HRH3 (0.45) | SIGMAR1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL11197419 | 0.69 | SIGMAR1 (0.68) | SIGMAR1ACHEALDH1A1USP2 | |
| SCHEMBL17285905 | 0.69 | SIGMAR1 (0.97) | SIGMAR1ACHEALDH1A1USP2 | |
| SCHEMBL22636376 | 0.68 | SIGMAR1 (0.43) | SIGMAR1L3MBTL1 | |
| SCHEMBL6570105 | 0.67 | SIGMAR1 (0.61) | SIGMAR1ACHEALDH1A1USP2NPC1 | |
| SCHEMBL152736 | 0.66 | ACHE (1.00) | SIGMAR1ACHEALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |