Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570100 | 0.86 | SIGMAR1 (0.51) | L3MBTL1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5713495 | 0.77 | HPGD (0.45) | L3MBTL1HPGDSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6570156 | 0.73 | SIGMAR1 (0.43) | SMN1; SMN2NPC1RAB9ASIGMAR1 | |
| SCHEMBL19850993 | 0.72 | L3MBTL1 (0.62) | L3MBTL1SIGMAR1 | |
| SCHEMBL7979173 | 0.72 | L3MBTL1 (0.62) | L3MBTL1SIGMAR1 | |
| SCHEMBL6570118 | 0.70 | MAPK1 (0.42) | L3MBTL1HPGDSMN1; SMN2ALDH1A1SIGMAR1 | |
| SCHEMBL6569758 | 0.69 | HRH3 (0.45) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6570124 | 0.68 | L3MBTL1 (0.52) | L3MBTL1HPGDSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL12725 | 0.68 | ACHE (0.66) | HPGDSMN1; SMN2SIGMAR1ACHE | |
| SCHEMBL11205656 | 0.68 | ACHE (0.66) | HPGDSMN1; SMN2SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |