Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169455 | 0.85 | — | — | |
| SCHEMBL21434195 | 0.83 | TSHR (0.36) | ALDH1A1MAOACYP3A4TDP1KMT2A | |
| SCHEMBL8773539 | 0.81 | LTA4H (0.57) | CA1CA2CA9MAOAKMT2A | |
| SCHEMBL1262460 | 0.76 | CA1 (0.47) | ALDH1A1CA1CA2CA9CYP1A2 | |
| SCHEMBL2404544 | 0.76 | NAAA (0.46) | ALDH1A1CA1CA2CA9CYP1A2 | |
| SCHEMBL10903374 | 0.76 | LTA4H (0.55) | CYP1A2CYP2C9CYP2C19LTA4H | |
| SCHEMBL4556133 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAOAMAOBMAPK1HSD17B10 | |
| SCHEMBL4556134 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAOAMAOBMAPK1HSD17B10 | |
| Biphenyl SCHEMBL7939259 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAOACYP1A2MAPK1CYP3A4 | |
| SCHEMBL28620636 | 0.73 | CYP1A2 (0.48) | ALDH1A1CA1CA2CA9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0615159-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2004-09-22 | — | — | EP | claimed |
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| US-9393306-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-06-18 | — | — | US | disclosed |
| WO-2013163321-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | YOU YOUNGJAE (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013163321-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | YOU YOUNGJAE (US) | 2013-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | PPOX, DUOX1, PAICS | ALDH1A1 977/4885CA1 201/4885CA2 563/4885 |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | PPOX, DUOX1, PAICS | ALDH1A1 977/4885CA1 201/4885CA2 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.