Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573765 | 0.90 | MAPK1 (0.49) | LTB4R2MAPK1PTPN11KDM4EALDH1A1 | |
| SCHEMBL6572946 | 0.85 | PTPN11 (0.42) | PTPN11GAAF2PRSS1PRSS2 | |
| SCHEMBL6574647 | 0.84 | PTGER1 (0.45) | PTPN11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574651 | 0.80 | LMNA (0.43) | LTB4R2PTPN11KDM4EALDH1A1GAA | |
| SCHEMBL6571441 | 0.80 | CYP3A4 (0.38) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6571371 | 0.80 | MAOA (0.34) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6572668 | 0.79 | RARB (0.43) | PTPN11ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL6572821 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL6574166 | 0.79 | MAP4K4 (0.42) | POLB | |
| SCHEMBL6572734 | 0.78 | FYN (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |