Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572946 | 0.93 | PTPN11 (0.42) | PTGER1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574651 | 0.88 | LMNA (0.43) | F2PRSS1PRSS2PRSS3ATR | |
| SCHEMBL6574642 | 0.84 | LTB4R2 (0.43) | F2PRSS1PRSS2PRSS3PTPN11 | |
| SCHEMBL6573765 | 0.82 | MAPK1 (0.49) | F2PRSS1PRSS2PRSS3CYP2C9 | |
| SCHEMBL6572668 | 0.81 | RARB (0.43) | F2PRSS1PRSS2PRSS3PTPN11 | |
| SCHEMBL6573465 | 0.79 | KMO (0.42) | PTGER1KMOPTPN11PLA2G2AFOLH1 | |
| SCHEMBL6571441 | 0.77 | CYP3A4 (0.38) | F2PRSS1PRSS2PRSS3CYP2C9 | |
| SCHEMBL6571124 | 0.77 | F2 (0.36) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6571371 | 0.77 | MAOA (0.34) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6572821 | 0.76 | ALDH1A1 (0.37) | HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |